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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFYVE16
All Species:
5.45
Human Site:
Y219
Identified Species:
15
UniProt:
Q7Z3T8
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z3T8
NP_001098721.1
1539
168849
Y219
D
T
T
L
S
D
S
Y
N
Y
S
G
T
E
N
Chimpanzee
Pan troglodytes
XP_001135982
1539
169040
Y219
D
T
T
L
S
D
S
Y
N
Y
S
G
R
E
N
Rhesus Macaque
Macaca mulatta
XP_001110183
1540
169100
C218
V
D
T
L
S
D
S
C
N
Y
S
G
T
E
N
Dog
Lupus familis
XP_536310
1516
166814
C218
D
T
T
A
S
D
S
C
N
Y
S
G
K
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q80U44
1528
166652
C215
D
M
A
L
F
D
S
C
K
Y
N
R
T
E
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510291
1525
166161
T212
K
S
C
N
H
L
D
T
A
F
L
D
S
S
D
Chicken
Gallus gallus
XP_424894
1103
120204
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396901
1227
137615
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781105
1601
173741
P234
Q
N
S
M
D
E
L
P
N
S
R
T
L
Q
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
94.3
82.8
N.A.
73.4
N.A.
N.A.
59.5
27.3
N.A.
N.A.
N.A.
N.A.
30.1
N.A.
25.1
Protein Similarity:
100
99.3
96.3
88.7
N.A.
82
N.A.
N.A.
73.2
41.3
N.A.
N.A.
N.A.
N.A.
48.7
N.A.
43.9
P-Site Identity:
100
93.3
80
80
N.A.
53.3
N.A.
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
93.3
80
80
N.A.
60
N.A.
N.A.
26.6
0
N.A.
N.A.
N.A.
N.A.
0
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
12
0
0
0
0
12
0
0
0
0
0
0
% A
% Cys:
0
0
12
0
0
0
0
34
0
0
0
0
0
0
0
% C
% Asp:
45
12
0
0
12
56
12
0
0
0
0
12
0
0
12
% D
% Glu:
0
0
0
0
0
12
0
0
0
0
0
0
0
56
0
% E
% Phe:
0
0
0
0
12
0
0
0
0
12
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
45
0
0
0
% G
% His:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
0
0
0
0
0
0
0
12
0
0
0
12
0
0
% K
% Leu:
0
0
0
45
0
12
12
0
0
0
12
0
12
0
0
% L
% Met:
0
12
0
12
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
0
12
0
0
0
0
56
0
12
0
0
0
56
% N
% Pro:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% P
% Gln:
12
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
12
12
12
0
0
% R
% Ser:
0
12
12
0
45
0
56
0
0
12
45
0
12
12
0
% S
% Thr:
0
34
45
0
0
0
0
12
0
0
0
12
34
0
0
% T
% Val:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
23
0
56
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _